I'm set up for Hi-Res audio. High speed USB to SMSL m100 mk.2. QED reference RCA cables to an Edifier M1390 2.1 speaker. I've gone for well designed Chi-Fi components with old old school UK designed interconnects.
So does Hi-Res make a difference? Absolutely! Comparing the same song at CD extracted 44.1 KHz 16 bit wav files to Hi-Res 192 KHz 24 bit wav files is like Chalk & Cheese. 😂
The nay Sayers have their systems set up wrong?